ASU special events management professor named to top 100 list

November 17, 2021

Erin Schneiderman once helped put on a Super Bowl in Arizona, and in 2021 the ASU clinical assistant professor arranged for her students help get people vaccinated outside stadiums. Her dedication and accomplishments in staging events and teaching special events management students just helped her score a touchdown for her career.

This month, Schneiderman was named to the list of this year’s Top 100 Influential People in the Event Industry. Schneiderman, who directs ASU’s Special Events Management program, joins a list of event professionals from 27 countries picked via an election in which 20,000 votes were cast. Portrait of Erin Schneiderman, clinical assistant professor in ASU's School of Community Resources and Development. Erin Schneiderman, clinical assistant professor in ASU's School of Community Resources and Development. Download Full Image

The awards are presented by Eventex Awards. The honors it has presented since 2009 represent “the most esteemed accolade in the world of events and experiential marketing, a true symbol of excellence,” according to its website. View the list of the top 100 here.

The list recognizes “the people who left a mark on the events world with their creativity, vision and capacity for innovation in 2021,” according to Eventex.

Since 2015, Schneiderman has taught in the ASU School of Community Resources and Development, based at the Watts College of Public Service and Community Solutions.

Her program trains students to become full-time event professionals, but it also prepares those who occasionally manage events as part of duties in other positions.

Before her career in education, Schneiderman put on events for both the NFL and the Thunderbird School of Global Management. She worked for the NFL’s Corporate Hospitality Village as an account manager from 2001–05. From 2005–08, she served on the Arizona Super Bowl Committee as its vice president of events. Then she went to work as director of special events at Thunderbird, which has since become part of ASU, serving until 2019.

When the COVID-19 pandemic hit, Schneiderman’s students were cut off from hands-on learning experiences due to widespread shutdowns. Her solution: She asked to include her students with ASU teams helping move thousands of people through Valley stadium parking lots to get vaccinated.

Schneiderman’s students worked more than 16,000 hours at two stadium sites in Phoenix and Glendale during the spring 2021 semester.

Earlier this year, the Watts College honored her with its 2021 Emerging Public Sector Educator Award.

School of Community Resources and Development Director and Associate Professor Christine Buzinde praised Schneiderman’s commitment to her students.

“Erin has worked very hard to ensure that students pursuing the Special Events Management Certificate program have numerous opportunities to engage in hands-on learning. She always actively involves special events students in multiple local events,” Buzinde said. “The fact that she was voted one of the top 100 most influential people in the event industry is great recognition of her service to the field, as well as her commitment to social-embedded practice.”

Schneiderman said the award tells her she is making a difference in the community.

"I love the idea that I can help shape the paths of aspiring event professionals with meaningful education,” Schneiderman said. “I am proud of the program that we have designed at ASU that combines in-class education with experiential learning. To be recognized on an international platform excites me for the future for our students."

Mark J. Scarp

Media Relations Officer, Watts College of Public Service and Community Solutions


Machine learning identifies mammal species with the potential to spread SARS-CoV-2

Insights can guide surveillance to prevent secondary spillover, new variants

November 17, 2021

Back-and-forth transmission of SARS-CoV-2 between people and other mammals increases the risk of new variants and threatens efforts to control COVID-19. A new study, published today in Proceedings of the Royal Society B, used a novel modeling approach to predict the zoonotic capacity of 5,400 mammal species, extending predictive capacity by an order of magnitude. Of the high-risk species flagged, many live near people and in COVID-19 hot spots.

A major bottleneck to predicting high-risk mammal species is limited data on ACE2, the cell receptor that SARS-CoV-2 binds to in animals. ACE2 allows SARS-CoV-2 to enter host cells and is found in all major vertebrate groups. It is likely that all vertebrates have ACE2 receptors, but sequences were only available for 326 species. Portrait of ASU Associate Professor Arvind Varsani Arvind Varsani is a virologist at the Biodesign Center for Fundamental and Applied Microbiomics and a researcher in the Center for Evolution and Medicine and the School of Life Sciences at ASU. Download Full Image

To overcome this obstacle, the team developed a machine learning model that combined data on the biological traits of 5,400 mammal species with available data on ACE2. The goal: to identify mammal species with high "zoonotic capacity" – the ability to become infected with SARS-CoV-2 and transmit it to other animals and people. The method they developed could help extend predictive capacity for disease systems beyond COVID-19.

The study was led by researchers at the Cary Institute of Ecosystem Studies. They are joined by João P.G.L.M. Rodrigues of Stanford University and Arvind Varsani of Arizona State University.

Varsani, a virologist at the Biodesign Center for Fundamental and Applied Microbiomics who contributed to the assembly of sequence data used in the study, commented, “This is a significant research outcome from a multidisciplinary team that includes animal and disease ecologists, structural biologist and a molecular and evolutionary virologist.”

Co-lead author Ilya Fischhoff, a postdoctoral associate at the Cary Institute of Ecosystem Studies, commented, “SARS-CoV-2, the virus that causes COVID-19, originated in an animal before making the jump to people. Now, people have caused spillback infections in a variety of mammals, including those kept in farms, zoos and even our homes. Knowing which mammals are capable of reinfecting us is vital to preventing spillback infections and dangerous new variants.”

When a virus passes from people to animals and back to people, it is called secondary spillover. This phenomenon can accelerate new variants establishing in humans that are more virulent and less responsive to vaccines. Secondary spillover of SARS-CoV-2 has already been reported among farmed mink in Denmark and the Netherlands, where it has led to at least one new SARS-CoV-2 variant.

Senior author and Cary Institute disease ecologist Barbara Han said, “Secondary spillover allows SARS-CoV-2 established in new hosts to transmit potentially more infectious strains to people. Identifying mammal species that are efficient at transmitting SARS-CoV-2 is an important step in guiding surveillance and preventing the virus from continually circulating between people and other animals, making disease control even more costly and difficult.”

Binding to ACE2 receptors is not always enough to facilitate SARS-CoV-2 viral replication, shedding and onward transmission. The team trained their models on a conservative binding strength threshold informed by published ACE2 amino acid sequences of vertebrates, analyzed using a software tool called HADDOCK (High Ambiguity Driven protein-protein DOCKing).

Ridgeline plots showing the distribution of predicted zoonotic capacity across mammals.

Ridgeline plots showing the distribution of predicted zoonotic capacity across mammals. Predicted probabilities for zoonotic capacity across the x-axis range from 0 (likely not susceptible) to 1 (zoonotic capacity predicted to be the same or greater than Felis catus), with the vertical line representing 0.5. The y-axis depicts all mammalian orders represented by the study's predictions. Points that were used to train the model are colored: Orange represents species with weaker predicted binding, and blue represents species with stronger predicted binding. Credit: Proceedings of the Royal Society B.

This software scored each species on predicted binding strength; stronger binding likely promotes successful infection and viral shedding.

Co-lead author and Cary Institute postdoctoral analyst Adrian Castellanos said, “The ACE2 receptor performs important functions and is common among vertebrates. It’s likely that it evolved in animals alongside other ecological and life history traits. By comparing biological traits of species known to have the ACE2 receptor with traits of other mammal species, we can make predictions about their capacity to transmit SARS-CoV-2.”

This combined modeling approach predicted zoonotic capacity of mammal species known to transmit with 72% accuracy and identified numerous additional mammal species with the potential to transmit SARS-CoV-2. Predictions matched observed results for white-tailed deer, mink, raccoon dogs, snow leopards and others. The model found that the riskiest mammal species were often those that live in disturbed landscapes and in close proximity to people – including domestic animals, livestock and animals that are traded and hunted.

The top 10% of high-risk species spanned 13 orders. Primates were predicted to have the highest zoonotic capacity and strongest viral binding among mammal groups. Water buffalo, bred for dairy and farming, had the highest risk among livestock. The model also predicted high zoonotic potential among live-traded mammals, including macaques, Asiatic black bears, jaguars and pangolins – highlighting the risks posed by live markets and wildlife trade.

SARS-CoV-2 also presents challenges for wildlife conservation. Infection has already been confirmed in Western lowland gorillas. For high-risk charismatic species like mountain gorillas, spillback infection could occur through ecotourism. Grizzly bears, polar bears and wolves, all in the 90th percentile for predicted zoonotic capacity, are frequently handled by biologists for research and management.

Han explained, “Our model is the only one that has been able to make risk predictions across nearly all mammal species. Every time we hear about a new species being found SARS-CoV-2 positive, we revisit our list and find they are ranked high. Snow leopards had a risk score around the 80th percentile. We now know they are one of the wildlife species that could die from COVID-19."

People working in close proximity with high-risk mammals should take extra precautions to prevent SARS-CoV-2 spread. This includes prioritizing vaccinations among veterinarians, zookeepers, livestock handlers and other people in regular contact with animals. Findings can also guide targeted vaccination strategies for at-risk mammals.

Han concluded, “We found that the riskiest mammal species are often the ones that live alongside us. Targeting these species for additional lab validation and field surveillance is critical. We should also explore underutilized data sources like natural history collections, to fill data gaps about animal and pathogen traits. More efficient iteration between computational predictions, lab analysis and animal surveillance will help us better understand what enables spillover, spillback and secondary transmission – insight that is needed to guide zoonotic pandemic response now and in the future.”

“Cross-disciplinary research like this is important to gain novel insights and is a collective learning endeavor for all involved, as each of us learns from the other field," Varsani said.

Varsani is also a researcher in the Center for Evolution and Medicine and the School of Life Sciences at ASU.

Authors were supported by various grants during the course of this work, including the National Institutes of Health, the National Science Foundation and the Defense Advanced Research Projects Agency.

Story written by the Cary Institute of Ecosystem Studies with co-author Richard Harth of ASU.

Richard Harth

Science writer, Biodesign Institute at ASU