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NIH grant to expand reach of autism study

ASU researcher seeks to diversify participant pool


January 23, 2024

The CDC estimates that more than 5 million adults in the United States have autism spectrum disorder (ASD), yet the condition and its effects on human cognition are still not fully understood.

“Autism as a diagnosis hasn't existed that long, and everyone thinks of autism as a childhood condition,” says B. Blair Braden, director of the Autism and Brain Aging Laboratory at Arizona State University.

Braden, an associate professor at ASU’s College of Health Solutions, has been researching autism and how it relates to memory challenges in adults since 2016. Thanks to a new grant from the National Institutes of Health (NIH), she will be able to expand upon an ongoing study that seeks to identify biomarkers and intervention targets in aging autistic adults.

According to the NIH, the research “will advance fundamental knowledge of brain aging vulnerabilities and mechanisms in ASD.”

The grant totals $3.3 million, with funds going toward staff salaries, equipment, participant compensation and hypothesis testing. The new funding will also allow the study to expand its reach into underrepresented communities where autism continues to be undiagnosed in many adults.

Two people looking at a computer screen as one gestures and speaks.
College of Health Solutions Associate Professor B. Blair Braden (right) has been awarded a grant from the National Institutes of Health to study autism spectrum disorder in adults. Photo courtesy the College of Health Solutions

Because of the hereditary nature of autism, Braden’s team often evaluates parents and grandparents of autistic children who suspect they are also on the spectrum.

“A lot of people that come to our study, they have been undiagnosed their whole life,” Braden said. “Their child or grandchild is diagnosed with autism, and through that process, they learn more about autism. They realize that they are probably autistic, and then we're able to evaluate them.”

Braden’s study is conducted through participant questionnaires, cognitive tasks and neuroimaging tasks using an MRI.

This latest source of funding buoys her hopes for what the study may be able to accomplish by allowing her to work directly with more people.

“It's the best part,” Braden said, “… to have that more immediate impact in making people's lives better.”

The Autism and Brain Aging Lab is currently looking for adults 18 years and older with or without autism to participate in the study. Call 480-727-3970, email abalab@asu.edu or visit the lab’s website for more information.

Story by Aidan Hansen, communications assistant, College of Health Solutions

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