NIH grant to expand reach of autism study


The CDC estimates that more than 5 million adults in the United States have autism spectrum disorder (ASD), yet the condition and its effects on human cognition are still not fully understood.

“Autism as a diagnosis hasn't existed that long, and everyone thinks of autism as a childhood condition,” says B. Blair Braden, director of the Autism and Brain Aging Laboratory at Arizona State University.

Braden, an associate professor at ASU’s College of Health Solutions, has been researching autism and how it relates to memory challenges in adults since 2016. Thanks to a new grant from the National Institutes of Health (NIH), she will be able to expand upon an ongoing study that seeks to identify biomarkers and intervention targets in aging autistic adults.

According to the NIH, the research “will advance fundamental knowledge of brain aging vulnerabilities and mechanisms in ASD.”

The grant totals $3.3 million, with funds going toward staff salaries, equipment, participant compensation and hypothesis testing. The new funding will also allow the study to expand its reach into underrepresented communities where autism continues to be undiagnosed in many adults.

Two people looking at a computer screen as one gestures and speaks.
College of Health Solutions Associate Professor B. Blair Braden (right) has been awarded a grant from the National Institutes of Health to study autism spectrum disorder in adults. Photo courtesy the College of Health Solutions

Because of the hereditary nature of autism, Braden’s team often evaluates parents and grandparents of autistic children who suspect they are also on the spectrum.

“A lot of people that come to our study, they have been undiagnosed their whole life,” Braden said. “Their child or grandchild is diagnosed with autism, and through that process, they learn more about autism. They realize that they are probably autistic, and then we're able to evaluate them.”

Braden’s study is conducted through participant questionnaires, cognitive tasks and neuroimaging tasks using an MRI.

This latest source of funding buoys her hopes for what the study may be able to accomplish by allowing her to work directly with more people.

“It's the best part,” Braden said, “… to have that more immediate impact in making people's lives better.”

The Autism and Brain Aging Lab is currently looking for adults 18 years and older with or without autism to participate in the study. Call 480-727-3970, email [email protected] or visit the lab’s website for more information.

Story by Aidan Hansen, communications assistant, College of Health Solutions

Downtown Phoenix campus, Faculty, SDG 03 Good Health and Well-Being, Community, Health and medicine, Health care, School of Life Sciences, Community involvement, The College of Liberal Arts and Sciences, College of Health Solutions

More Health and medicine

 

Smiling baby reaching toward avocados on a high-chair tray while a woman in a blue dress holds the tray.

Arizona babies take a bite out of research

Like many parents, Megan Rivas wants to give her 6-month-old daughter, Monroe, a healthy start, and one of the ways she’s going about it could make a big difference for more than just her daughter.…

On the left, a Tsimane women makes chicha. On the right, Hadza men drink water.

Gut microbes across continents trace ancient human migration

As humans left Africa tens of thousands of years ago, eventually populating the entire planet, they were joined on their world-conquering ride by the trillions of microorganisms that compose the gut…

Woman sitting on the floor, looking sad while leaning against a crib.

Care before crisis

The recent murder trial of Lindsay Clancy, a Massachusetts mother accused of killing her three children, focused national attention on maternal mental health and the structures — or lack thereof — we…